Leukopenia exists
whenever the number of the white blood cells in the peripheral
circulation is continually lower than 4¡Á109/L, and
the percentage of neutrophilic granulocytes is normal or
slightly decreased. In most cases, the disease is related to the
decrease of neutrophilic granulocytes, and granulocytopenia is
defined as the absolute number of granulocytes is reduced below
1.8¡ª2¡Á109/L. In TCM, this disease is grouped into
the categories of "xuan yun" (vertigo), "xu lao" (consumptive
diseases), etc.
Main
Points of Diagnosis
1. There
must be a history of facilitating the result of leukopenia, e.g.
contact with X-ray or radioactive materials, administration of
drugs that affect leucocytes ,such as Amidopy-rine, Butazolidin,
Thiouracil, Sulfonamides and antitumor agents, etc. Virus
infection, desmosis and hepersplenism may also cause leukopenia.
2. The patient may be
sick with such symptoms as dizziness, fatigue, mild fever,
amprexoa and insomnia. The disease is chronic and is frequently
accompanied with infections.
3. Leukocyte count
ranges 2¡ª4¡Á109/L, with normal or slightly reduced
percentage of granulocytes. The picture of bone marrow shows no
specific change.
4. The provocative test
of adrenalin is helpful for identifying the false leukopenia.
Hydrocortisone test can be used to test the reserving energy of
bone marrow, indicating treatment and prognosis.
Differentiation and Treatment of Common Syndromes
1.
Deficiency of Both Qi and Yin
Main Symptoms and Signs:
Dim complexion, dizziness, blurred vision, lassitude and
weakness, dysphoria with feverish sensation in the chest, palms
and soles, pink tongue with little fur, thready and weak or
thready and rapid pulse.
Therapeutic Principle:
Supplementing qi and nourishing yin.
Recipe: Pulse-Activating
Powder with additional ingredients.
pseudostellaria root
ophiopogon root
schisandra berry
astragalus root,
siberian solomonseal
rhizome
spatholobus stem
tortoise plastron
prepared licorice
All the above herbs are
to be decocted in water for oral administration.
In addition to the above
ingredients, drugs of prepared rehmannia root 15g, dogwood fruit
12g and wolfberry fruit 15g are needed for cases with severe
deficiency of the liver-yin and kidney-yin marked by amnesia,
tinnitus, soreness and weakness in the loins and knees, tidal
fever, night sweat, etc.
2. Insufficiency of Both
the Spleen and Stomach
Main Symptoms and Signs:
Vertigo, emaciation, lassitude, anorexia, indigestion, abdominal
distension and fullness, sallow complexion, loose stool, pale
tongue with whitish fur, thready and weak pulse.
Therapeutic Principle:
Strengthening the spleen and replenishing qi.
Recipe: Modified
Prescriptions of Decoction of Four Noble Herbs and Astragalus
Decoction for Tonifying the Middle-Warmer.
codonopsis
root
white atractylodes
rhizome
poria
prepared licorice
astragalus root
cinnamon twig
white peony root
Chinese date
hyacinth bean
Chinese yam
amommum fruit
chicken's gizzard
All the above herbs are
to be decocted in water for oral administration.
3. Deficiency of the
Spleen-Yang and Kidney-Yang
Main Symptoms and Signs:
Dizziness, tinnitus ,fatigue and weakness, deficiency of qi
,disinclination to talk, intolerance of cold, cold limbs, aching
pain and weakness in the loins and knees, poor appetite, loose
stool, or puffy face and edema of limbs, pale and tender tongue
with thin and whitish or whitish and greasy fur, deep, thready
and weak pulse.
Therapeutic Principle:
Warming and replenishing the spleen and kidney.
Recipe: Modified
Prescriptions of Aconite Decoction for Regulating the Function
of Middle-Warmer and Kidney-Yang Reinforcing Bolus.
prepared aconite root
dried ginger
codonopsis root
white atractylodes
rhizome
poria
eucommia bark
antler glue (melted in
boiling water)
dodder seed
astragalus root
prepared licorice
All the
above herbs are to be decocted in water for oral administration.
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